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10.9.2008 9:05 AM

Bisphenol-A May Disrupt Cancer Treatment

Breast Cancer Cell Study Finds That, Like Estrogen, Bisphenol-A Protects Cancer Cells

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By Dan Shapley

New science raises yet another concern about Bisphenol-A, the controversial ingredient in many plastics and in the lining of cans. Bisphenol-A mimics the female hormone estrogen, and has been implicated in a range of diseases and disorders by independent scientists whose work runs counter to official government pronouncements about the chemical's safety.

The new University of Cincinnati study says that Bisphenol-A may reduce the effectiveness of chemotherapy treatments. Bisphenol-A seems to bolster proteins that protect cancer cells, according to the research, published in the peer-reviewed journal Environmental Health Perspectives.

Bisphenol-A is not only similar to estrogen, but to a cancer-promoting compound called diethylstilbestrol (DES). DES makes cancer cells proliferate, but Bisphenol-A seems to protect cells from chemical attack, as does estrogen.

The researchers did the laboratory work on breast cancer cells.


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