2011 Toyota Prius
Fuel economy: 50 mpg
Annual fuel cost: $888
Annual CO2: 3.8 tons
The venerable midsize family sedan is synonymous with hybrids, and it still leads the pack. Further, Consumer Reports has said that it beats the Nissan Leaf and the Chevrolet Volt in value, even though it takes about twice as much gas to get around in it.
Good Housekeeping selected the Prius as its best choice for a high-MPG car, lauding its "good performance with optimal gas mileage for city driving in particular."